Friday, March 29, 2024

Razib Khan's Unsupervised Learning podcast


Recent interview with Razib Khan. We've known each other IRL for about 20 years now, so this conversation has a slightly different character than other interviews I've done. 

I highly recommend his substack and podcast, particularly if you are interested in ancient DNA, human evolution, deep history.

Thursday, March 21, 2024

Russell Clark: Japan, China, and USD reserve status — Manifold #56


Russell Clark is a hedge fund investor who has lived and worked in both Japan and China. He writes the widely followed Substack Capital Flows and Asset Markets: 

Steve and Russell discuss: 

0:00 Introduction 
0:52 Russell's background and experiences in Japan 
13:25 Hong Kong and finance 
31:53 China property bubble 
48:54 Dollar status as global reserve currency 
56:09 Japan and China economies from a long run perspective 
1:05:07 Inflation, US economy, and macro observations 

Monday, March 11, 2024

Solving the Hallucination Problem - interview with AppliedAI


Recent podcast interview with AppliedAI. 

We discuss Enterprise GPT. 

Good intro to how customer-defined AI/LLM memory eliminates hallucinations.

Thursday, March 07, 2024

Stephen Grugett: Predicting the Future with Manifold Markets — Manifold #55


Stephen Grugett is the co-founder of Manifold Markets, the world's largest prediction market platform where people bet on politics, tech, sports, and more. 

Steve and Stephen discuss: 

0:00 Introduction 
0:52 Stephen Grugett’s background 
5:20 The genesis and mission of Manifold Markets 
11:25 The play money advantage: Legalities and user engagement 
20:47 Manifold’s user base and the power of calibration 
23:35 Simplifying prediction markets for broader engagement 
27:31 Revenue streams and future business directions 
30:46 Legal challenges in prediction markets 
31:47 Dating markets 
32:53 The Art of PR 
38:32 Global reach and community engagement 
39:27 The future of Manifold Markets and user predictions 
43:38 Life in the Bay Area; Tech, culture, and crazy stuff 

Manifold Markets:

Elizabeth Carr (first US IVF baby) and Genomic Prediction in WSJ

Elizabeth Carr (first US IVF baby) and Genomic Prediction in the Wall Street Journal.
Elizabeth Carr has always been a living symbol of fertility technology’s possibilities. Now she is the face of its challenges. 
Carr, 42 years old, is the first baby born by in vitro fertilization in the U.S. Over the years she has told countless audiences how the technology made it possible for her mother to have a baby. 
In the weeks since Alabama’s Supreme Court ruled that frozen embryos should be considered children, Carr has called for protections around IVF procedures—extracting eggs, fertilizing them in a lab and transferring an embryo into a uterus—that now account for some 2% of U.S. births annually. 
Sen. Tim Kaine (D., Va.) said federal legislation backing IVF access would “enable the Elizabeth Carrs of the world to continue to be born.” Kaine invited Carr to accompany him on Thursday to President Biden’s State of the Union address. 
“My life gives people hope,” Carr said. 
The Alabama ruling is galvanizing Carr’s work in another way. Carr leads public relations and patient advocacy at Genomic Prediction, which sells genetic tests to screen embryos. Doctors can order tests for patients who want to screen for diseases and abnormalities or get an overall embryo health score. Patients and doctors can use the results to decide which embryos to transfer. Unused embryos can be stored for years. Some get discarded. ...

A conversation with Elizabeth

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