It doesn't seem like a lot of saliva, but it took some work to reach the fill line. Ready to go!
Pessimism of the Intellect, Optimism of the Will Favorite posts | Manifold podcast | Twitter: @hsu_steve
Thursday, May 31, 2012
Do not eat this kit
I'm one of the laggards in returning my DNA kit. It's been sitting on my desk for months -- a miracle that my kids haven't ripped it apart by now. To volunteer, see here.
It doesn't seem like a lot of saliva, but it took some work to reach the fill line. Ready to go!
Unofficially, and off the record, some genotyping is going to happen in late summer. Nuff said.
It doesn't seem like a lot of saliva, but it took some work to reach the fill line. Ready to go!
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14 comments:
What is the male:female ratio of eligibility based on automatic qualifying criteria? It seems the criteria would skew even more heavily male than the natural population.
I wonder if Steve set the admission criteria to assure his own admission.
If I sent in my dog's saliva would you be able to tell?
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My sample laid around the house for at least a month before I got myself organized enough to mail it. Fortunately, Oragene's FAQ reports that their collection kits are still usable after over a year at room temperature.
Will the initial round of genotyping be able to detect CNVs? I had mine sequenced through 23andme, but their tech didn't do CNVs or deletions. I wonder if I'll get anything out of this or if I volunteered my DNA out of the goodness of my heart.
A. The goodness of you heart.
Unofficially, and off the record, we will be doing whole genome sequencing instead of SNPs. So you will eventually get a lot more information than you did from 23andMe. You will likely be among the first 10k or so humans to be sequenced at this level of coverage.
that's badass. any idea yet when we could expect results?
Runs scheduled for Sept 2012. Will take a while to process and clean data.
I admit I was distressed to learn that the samples had not even been sent to Hong Kong yet. Thanks for some positive news.
That's awesome!
http://ukpmc.ac.uk/abstract/MED/8883493
Another example of why this study will probably be useless and meaningless except of course for indeological purposes.
Better compare the DNA of standard poodles to Afghans. Dog breeds do have genetically determined psychological traits in my experience.
Totally tubular.
A run to sequence whole human genome takes roughly 10 days on Illumina's HiSeq. With roughly 100 machines, that's 300 genomes per month. Your stated goal is N >3000 IIRC, so it sounds like a year worth of sequencing alone.
Your estimates seem way too high. Also keep in mind the coverage level.
600 GB/wk is doable now, which is many complete human genomes per week on a single machine.
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