Thursday, January 22, 2009

Genetic substructure of Ashkenazim

More principal components results from the huge space of human genetic variation.







Figures from the paper below (additional labeling by Razib).

A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans

Anna C Need, Dalia Kasperaviciute, Elizabeth T Cirulli and David B Goldstein

Genome Biology 2009, 10:R7doi:10.1186/gb-2009-10-1-r7

Conclusions: Here we show that within Americans of European ancestry there is a perfect genetic corollary of Jewish ancestry which, in pinciple, would permit near perfect genetic inference of Ashkenazi Jewish ancestry. In fact, even subjects with a single Jewish grandparent can be statistically distinguished from those without Jewish ancestry. We also found that subjects with Jewish ancestry were slightly more heterozygous than the subjects with no Jewish ancestry, suggesting that the genetic distinction between Jews and non-Jews may be more attributable to Near-Eastern origin for Jewish popuations than to population bottlenecks.

Blog Archive

Labels