Wednesday, December 17, 2008

More genetic substructure

Via Genetic Future, two more principal components analyses of SNP data. Click the genetics label for related posts.

European, Nigerian and East Asian samples from HapMap and 100 African-American samples clustered based on data from ~600,000 genetic markers. The bend toward the East Asian cluster is probably due to Native American admixture.

Alkes L. Price, Nick Patterson, et al. (2008). Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans, PLoS Genetics, 4 (12) DOI: 10.1371/journal.pgen.1000294.

Resolving Finns and Swedes. Jakkula et al. (2008) The Genome-wide Patterns of Variation Expose Significant Substructure in a Founder Population, The American Journal of Human Genetics, 83 (6), 787-794 DOI: 10.1016/j.ajhg.2008.11.005.

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