Steve answers questions about recent progress in AI/ML prediction of
complex traits from DNA, and applications in embryo selection.
Highlights:
1. Overview of recent advances in trait prediction
2. Would cost savings from breast cancer early detection pay for
genotyping of all women?
3. How does IVF work? Economics of embryo selection
4. Whole embryo genotyping increases IVF success rates (pregnancy per
transfer) significantly
5. Future predictions
Some relevant scientific papers:
Preimplantation Genetic Testing for Aneuploidy: New Methods and Higher Pregnancy Rates
2021 review article on complex trait prediction
Accurate Genomic Prediction of Human Height
Genomic Prediction of 16 Complex Disease Risks Including Heart Attack,
Diabetes, Breast and Prostate Cancer
Genetic architecture of complex traits and disease risk predictors
Sibling validation of polygenic risk scores and complex trait prediction
No comments:
Post a Comment