A great MIT colloquium by Jim Simons (intro by I. Singer). Interesting discussion @28 min about how Simons (after leaving mathematics at 38) became an investor. Initially, he relied both on fundamental / event-driven analysis (reading the newspaper ;-) as well as computer models. But Simons eventually decided on a completely model-driven approach, and the rest is history.
@38 min: on RenTech's secret, We start with first rate scientists ... Great infrastructure ... New ideas shared and discussed as soon as possible in an open environment ... Compensation based on overall firm performance ...
@44 min: Be guided by beauty ... Try to do it RIGHT ... Don't give up and hope for some good luck!
@48 min: a defense of HFT ... the cost of liquidity?
@55 min: world's greatest investor is a Keynesian :-)
@58 min: brief precis of financial crisis ... See also here.
See also Jim Simons is my hero.