omicsmaps.com shows the locations of next-gen sequencing devices around the world. The map below is of Illumina HiSeqs -- note the 137 at BGI. As far as I can tell the other big concentration is 50 at the Broad Institute. The Wellcome Trust Sanger Institute (Cambridge, UK) has 23. Click for larger version.
Two more nice figures from MIT Technology Review. Click for larger version.
Steve, do you see anything preventing this from happening? Any thoughts as to why it has not happened yet? "Harvard geneticist George Church says that eventually only the differences between a newly sequenced genome and a reference genome will need to be stored. That information could be encoded in as little as four megabytes." (from the linked article)
ReplyDeleteChurch is correct. At the moment there are probably reasons to store the raw data because of sequencing errors, etc.
ReplyDeleteI have participated in sequencing over the years, and I think that we still aren't 100% sure of any of the whole genome sequences. For mtDNA we do have a "certain" reference, but that is just a tiny bit of DNA ... The process is messy, messy, messy .... Is there any browser out there that will let me point-and-click at a chromosome and scroll along and look at the reference base pairs? I think we still have a few things to nail down .... but not 100% sure ... Dr. Hsu?
ReplyDeleteSpeaking of sequencing genomes, any news on the progress on sequencing in the BGI Congnitive Genomics study? My status has been the same for months: "Thanks for sending us your saliva sample! We've received it, and are currently preparing to sequence it. We estimate that we'll have results for you sometime in the fall or winter."
ReplyDeleteAs an aside: I came across your blog via links from the study and am now a regular visitor. Great stuff! Although as a Caltech alum and Michigander, it pains me to see that MSU got you rather than UMich. :-)
Stay tuned -- we recently started sequencing our samples!
ReplyDeleteMy uninformed Caltech grad self initially confused UMich with MSU ...
ReplyDelete