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Pessimism of the Intellect, Optimism of the Will     Favorite posts | Manifold podcast | Twitter: @hsu_steve

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Steve Hsu
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Thursday, February 16, 2023

Bing vs. Bard, US-China STEM Competition, and Embryo Screening — Manifold Episode #30

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  Steve discusses the AI competition between Microsoft and Google, the competition between the U.S. and China in STEM, China’s new IVF polic...
Thursday, February 02, 2023

ChatGPT, LLMs, and AI — Manifold #29

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  Steve discusses Large Language Model AIs such as ChatGPT.  0:00 How do LLMs work?  10:22 Impact of ChatGPT  15:21 AI landscape  24:13 Hall...
Thursday, January 19, 2023

Dominic Cummings: Vote Leave, Brexit, COVID, and No. 10 with Boris — Manifold #28

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  Dominic Cummings is a major historical figure in UK politics. He helped save the Pound Sterling, led the Vote Leave campaign, Got Brexit D...
Thursday, January 05, 2023

Sahil Lavingia: Founding Gumroad, The Minimalist Entrepreneur, and our AI LLM future — Manifold #27

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  Sahil Lavingia founded Gumroad at the age of 19 and built it into a leading digital commerce platform. He is the author of The Minimalist ...
Friday, December 23, 2022

Peace on Earth, Good Will to Men 2022

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When asked what I want for Christmas, I reply: Peace On Earth, Good Will To Men :-) No one ever seems to recognize that this comes from...
Thursday, December 15, 2022

Geoffrey Miller: Evolutionary Psychology, Polyamorous Relationships, and Effective Altruism — Manifold #26

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  Geoffrey Miller is an American evolutionary psychologist, author, and a professor of psychology at the University of New Mexico. He is kno...
Monday, December 05, 2022

Decoherence and Quantum Measurement: The Missing Lecture

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This is an elementary lecture for students which discusses quantum measurement from the modern perspective of decoherence. Decoherence and...
Thursday, December 01, 2022

Anna Krylov: The Politicization of Science in Academia — Manifold #25

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  Anna I. Krylov (Russian: Анна Игоревна Крылова) is Professor of Chemistry at the University of Southern California (USC), working in the f...
Thursday, November 17, 2022

Abdel Abdellaoui: Genetics, Psychiatric Traits, and Educational Attainment — Manifold #24

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  Abdel Abdellaoui is Assistant Professor of Genetics in the Department of Psychiatry, Amsterdam UMC, University of Amsterdam.  Abdel Abdell...
Sunday, November 13, 2022

Smart Leftists vs Dumb Leftists

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Smart Leftists vs Dumb Leftists: Who qualifies as former? How about Soros, the top donor to the Democratic Party? A few years ago I gave a t...
Monday, November 07, 2022

Nozick and Leftists

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From this interview with Robert Nozick : I had been at Harvard as an Assistant Professor in the mid-​sixties and then came back in 1969 as a...
Thursday, November 03, 2022

Richard Sander on SCOTUS Oral Arguments: Affirmative Action and Discrimination against Asian Americans at Harvard and UNC (Manifold #23)

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  Richard Sander is Jesse Dukeminier Professor at UCLA Law School. AB Harvard, JD, PhD (Economics) Northwestern.  Sander has studied the str...
Tuesday, October 25, 2022

American Society of Human Genetics (ASHG) 2022 Posters

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New results from Taiwan Precision Medicine Initiative, a mega-biobank (>500k already genotyped). Diabetes predictor trained in TW as powe...
Thursday, October 20, 2022

Discovering the Multiverse: Quantum Mechanics and Hugh Everett III, with Peter Byrne — Manifold #22

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  Peter Byrne is an investigative reporter and science writer based in Northern California. His popular biography, The Many Worlds of Hugh E...
Saturday, October 15, 2022

Times of Israel on Polygenic Embryo Screening

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This is a very nice article on polygenic embryo screening and its prospects in Israel. Worth reading in full. Leading statistical genetici...
Thursday, October 06, 2022

Jeffrey Sachs: Lessons from the COVID Commission, Lab Leak Questions, and Nord Stream — Manifold Episode 21

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  Jeffrey D. Sachs is a world-renowned economics professor, bestselling author, innovative educator, and global leader in sustainable develo...
Tuesday, October 04, 2022

SAT score distributions in Michigan

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The state of Michigan required all public HS seniors to take the SAT last year (~91k out of ~107k total seniors in the state). This generate...
Wednesday, September 28, 2022

The Future of Human Evolution -- excerpts from podcast interview with Brian Chau

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The transcript excerpts below are from my recent conversation with Brian Chau (aka Cactus Chu) on his podcast. Segments begin at 47m and 1h0...
Tuesday, September 27, 2022

Quantum Hair in Electrodynamics and Gravity (arXiv:2209.12798)

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New paper! Quantum Hair in Electrodynamics and Gravity   Xavier Calmet, Stephen D. H. Hsu  arXiv:2209.12798  We demonstrate the ex...
Thursday, September 22, 2022

Rob Henderson: A Journey from Foster Care to the US Military to Elite Academia — Manifold podcast #20

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  Rob Henderson grew up in foster homes in California, joined the Air Force at 17, attended Yale on the G.I. Bill, and is currently a Gates ...
Tuesday, September 20, 2022

Sibling Variation in Phenotype and Genotype: Polygenic Trait Distributions and DNA Recombination Mapping with UK Biobank and IVF Family Data (medRxiv)

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This is a new paper which uses Genomic Prediction IVF family data, including genotyped embryo samples. Sibling Variation in Phenotype and G...
Thursday, September 08, 2022

Lyle Goldstein on U.S. Strategic Challenges: Russia, China, Ukraine, and Taiwan — Manifold #19

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  Professor Goldstein recently retired after 20 years of service on the faculty of the U.S. Naval War College (NWC). During his career at NW...
Monday, September 05, 2022

Lunar Society (Dwarkesh Patel) Interview

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  Dwarkesh did a fantastic job with this interview. He read the scientific papers on genomic prediction and his questions are very insightfu...
Thursday, August 25, 2022

Harvard Veritas: interview with a recent graduate (anonymous) — Manifold Episode #18

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  The guest for this episode is a recent graduate of Harvard College, now pursuing a STEM PhD at another elite university. We have withheld ...
Friday, August 19, 2022

Geostrategy and US-China Military Competition

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I've been asked to write something about PRC military buildup and a potential Taiwan (TW) conflict.  1. My perspective and bona fides: M...
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