tag:blogger.com,1999:blog-5880610.post2388741946226800607..comments2024-01-13T18:57:18.243-05:00Comments on Information Processing: Rare mutations and severe intellectual disabilitySteve Hsuhttp://www.blogger.com/profile/02428333897272913660noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-5880610.post-51574518819297334262014-06-10T13:18:39.530-04:002014-06-10T13:18:39.530-04:00http://en.wikipedia.org/wiki/Common_cause_and_spec...http://en.wikipedia.org/wiki/Common_cause_and_special_cause_(statistics)<br />Seems we can learn from the special cause variation on either tail. It is just as well to look for the anchors that hold us back as to look for the rockets that shoot us up. The goal is to learn from those so we can shift the mean up for the common cause variation.Bobdisqusnoreply@blogger.comtag:blogger.com,1999:blog-5880610.post-18624170182912322662014-06-07T03:59:14.834-04:002014-06-07T03:59:14.834-04:00Nice article.
You had stated that these low abill...Nice article.<br /><br />You had stated that these low abillity individuals account for 0.5% of new borns. Could this mean that the are the 1 in 200 embryos whom experienced really unfair genetic crossover during meiosis(in regards to cognition). If embryos can exibit a normal distribution(of course) then doesn't it mean that 1 in 200 embros are also at iq 150? If so then could embryo Butchhttps://www.blogger.com/profile/02031462543353967826noreply@blogger.comtag:blogger.com,1999:blog-5880610.post-65726011957389606262014-06-06T19:56:53.106-04:002014-06-06T19:56:53.106-04:00It may yield clues as you say, but it may also cau...It may yield clues as you say, but it may also cause wild goose chases. I defenitely agree that looking at cognitive outliers (high or low) is an excellent way to find IQ genes, but in my humble speculative opinion, a more efficient approach might be to look only at familial outliers and not at organic outliers.<br /><br />The reason is people with a familial IQ below 50 are outliers only with Pumpkinperson.comnoreply@blogger.comtag:blogger.com,1999:blog-5880610.post-56875083411516830582014-06-06T17:28:25.758-04:002014-06-06T17:28:25.758-04:00Mutations of large effect may yield clues about im...Mutations of large effect may yield clues about impairment of cognition (i.e., molecular mechanisms). That may help to identify variants of smaller negative effect ("nicks") in the future.steve hsuhttp://duende.uoregon.edu/noreply@blogger.comtag:blogger.com,1999:blog-5880610.post-55503555590538474662014-06-06T17:06:15.242-04:002014-06-06T17:06:15.242-04:00The problem with studying people with IQ's bel...The problem with studying people with IQ's below 50 is that their disabilities are likely to be organic rather than familial and thus not part of the biologically normal variation in IQ. It is for this reason that there are more people with IQ's below 50 than the normal curve predicts; the normal curve is includes only the biologically normal population since the standardization samples Pumpkinperson.comnoreply@blogger.com